NALCN 抗体 (AA 1659-1738)
Quick Overview for NALCN 抗体 (AA 1659-1738) (ABIN1686626)
抗原
See all NALCN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1659-1738
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特异性
- Detects ~200 kDa.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
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亚型
- IgG1
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anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (HRP)
NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 HRP
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (FITC)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 FITC
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (Biotin)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 Biotin
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (PE)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 PE
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (PerCP)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 PerCP
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (APC)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 APC
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (Atto 488)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 Atto 488
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (Atto 594)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 Atto 594
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 1659-1738) antibody (Atto 390)NALCN 适用: 大鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S187-7 Atto 390
anti-Sodium Leak Channel, Non-Selective (NALCN) (AA 902-914), (Extracellular) antibodyNALCN 适用: 大鼠 WB, IF, IHC, IC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN1686626 was sufficient for detection of NALCN in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- -20°C
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- NALCN (Sodium Leak Channel, Non-Selective (NALCN))
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别名
- NALCN
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背景
- NALCN (sodium leak channel non-selective protein), alsoknown as CanIon or VGCNL1 (voltage gated channel-like protein 1), is a 1738 amino acid multi-pass membrane protein that belongs to the cation-nonselective channel family. NALCN is highly conserved in mammals and is widely expressed in the central nervous system. Activated by NK-1R, NALCN is a voltage-independent, nonselective cation channel which is permeable to sodium, potassium and calcium ions. NALCN is responsible for background sodium ion leak conductance in neurons and regulates basal excitability of the nervous systems. Defects of NALCN in mice causes disruption in respiratory rhythm and death occurs within 24 hours of birth. Three isoforms of NALCN exists due to alternative splicing events.
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基因ID
- 266760
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NCBI登录号
- NP_705894
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UniProt
- Q6Q760
抗原
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