UCP2 抗体
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北京 101111
Quick Overview for UCP2 抗体 (ABIN1683207)
抗原
See all UCP2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- A synthetic peptide of human UCP2
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
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别名
- UCP2
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背景
- Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.,UCP2,BMIQ4,SLC25A8,UCPH,Cancer,Endocrine & Metabolism,Warburg Effect,Endocrine and metabolic diseases,Obesity,UCP2
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分子量
- 33 kDa
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基因ID
- 7351
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UniProt
- P55851
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途径
- Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport
抗原
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