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TDP1 抗体 (AA 1-140)

This anti-TDP1 antibody is a 兔 多克隆 antibody detecting TDP1 in WB 和 IF. Suitable for 人.
产品编号 ABIN1682992
发货至: 中国

Quick Overview for TDP1 抗体 (AA 1-140) (ABIN1682992)

抗原

See all TDP1 抗体
TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TDP1 antibody is un-conjugated

应用范围

  • 32
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-140

    序列

    MSQEGDYGRW TISSSDESEE EKPKPDKPST SSLLCARQGA ANEPRYTCSE AQKAAHKRKI SPVKFSNTDS VLPPKRQKSG SQEDLGWCLS SSDDELQPEM PQKQAEKVVI KKEKDISAPN DGTAQRTENH GAPACHRLKE

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TDP1 (NP_060789.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

    别名

    TDP1

    背景

    The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).,TDP1,Epigenetics & Nuclear Signaling,Cancer,Drug resistance,Topoisomerases,TDP1

    分子量

    41 kDa/68 kDa

    基因ID

    55775

    UniProt

    Q9NUW8
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