STAT4 抗体 (AA 600-700)
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北京 101111
Quick Overview for STAT4 抗体 (AA 600-700) (ABIN1682909)
抗原
See all STAT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 600-700
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序列
- SESHLGGITF TWVDHSESGE VRFHSVEPYN KGRLSALPFA DILRDYKVIM AENIPENPLK YLYPDIPKDK AFGKHYSSQP CEVSRPTERG DKGYVPSVFI P
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 600-700 of human STAT4 (NP_001230764.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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别名
- STAT4
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背景
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.,STAT4,SLEB11,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,STAT4
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分子量
- 85 kDa
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基因ID
- 6775
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UniProt
- Q14765
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途径
- JAK/STAT Signaling
抗原
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