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PKN1 抗体 (AA 1-300)

This anti-PKN1 antibody is a 兔 多克隆 antibody detecting PKN1 in WB. Suitable for 人.
产品编号 ABIN1682293
发货至: 中国

Quick Overview for PKN1 抗体 (AA 1-300) (ABIN1682293)

抗原

See all PKN1 抗体
PKN1 (Protein Kinase N1 (PKN1))

适用

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宿主

  • 22
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克隆类型

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多克隆

标记

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This PKN1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-300

    序列

    MASDAVQSEP RSWSLLEQLG LAGADLAAPG VQQQLELERE RLRREIRKEL KLKEGAENLR RATTDLGRSL GPVELLLRGS SRRLDLLHQQ LQELHAHVVL PDPAATHDGP QSPGAGGPTC SATNLSRVAG LEKQLAIELK VKQGAENMIQ TYSNGSTKDR KLLLTAQQML QDSKTKIDII RMQLRRALQA GQLENQAAPD DTQGSPDLGA VELRIEELRH HFRVEHAVAE GAKNVLRLLS AAKAPDRKAV SEAQEKLTES NQKLGLLREA LERRLGELPA DHPKGRLLRE ELAAASSAAF

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PKN1 (NP_002732.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PKN1 (Protein Kinase N1 (PKN1))

    别名

    PKN1

    背景

    The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.,PKN1,DBK,PAK-1,PAK1,PKN,PKN-ALPHA,PRK1,PRKCL1,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,PKN1

    分子量

    104 kDa

    基因ID

    5585

    UniProt

    Q16512
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