NQO1
适用: 人, 小鼠, 大鼠
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
应用备注
WB,1:500 - 1:2000,IF,1:50 - 1:200
限制
仅限研究用
缓冲液
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
NQO1
(NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
别名
NQO1
背景
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,DHQU,DIA4,DTD,NMOR1,NMORI,QR1,NQO1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,NQO1