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KISS1 抗体

This anti-KISS1 antibody is a 兔 多克隆 antibody detecting KISS1 in WB 和 IHC. Suitable for 人.
产品编号 ABIN1680598
发货至: 中国

Quick Overview for KISS1 抗体 (ABIN1680598)

抗原

See all KISS1 抗体
KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

适用

  • 35
  • 16
  • 5

宿主

  • 34
  • 6

克隆类型

  • 35
  • 5
多克隆

标记

  • 29
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KISS1 antibody is un-conjugated

应用范围

  • 23
  • 14
  • 13
  • 7
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide of human KISS1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

    别名

    KISS1

    背景

    This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.,KISS1,HH13,KiSS-1,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,Neuroscience,KISS1

    分子量

    14 kDa

    基因ID

    3814

    UniProt

    Q15726

    途径

    Positive Regulation of Peptide Hormone Secretion
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