KIFAP3 抗体 (AA 1-200)
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北京 101111
Quick Overview for KIFAP3 抗体 (AA 1-200) (ABIN1680591)
抗原
See all KIFAP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-200
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序列
- MQGEDARYLK RKVKGGNIDV HPSEKALIVH YEVEATILGE MGDPMLGERK ECQKIIRLKS LNANTDITSL ARKVVEECKL IHPSKLNEVE QLLYYLQNRR DSLSGKEKKE KSSKPKDPPP FEGMEIDEVA NINDMDEYIE LLYEDIPDKV RGSALILQLA RNPDNLEELL LNETALGALA RVLREDWKQS VELATNIIYI
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KIFAP3 (NP_055785.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))
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别名
- KIFAP3
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背景
- The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.,KIFAP3,FLA3,KAP-1,KAP-3,KAP3,SMAP,Smg-GDS,dJ190I16.1,Epigenetics & Nuclear Signaling,KIFAP3
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分子量
- 82 kDa/86 kDa/91 kDa
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基因ID
- 22920
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UniProt
- Q92845
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途径
- Hedgehog Signaling, Sensory Perception of Sound
抗原
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