GFRA2 抗体 (AA 360-464)
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北京 101111
Quick Overview for GFRA2 抗体 (AA 360-464) (ABIN1679988)
抗原
See all GFRA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 360-464
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序列
- DVNVSPKGPS FQATQAPRVE KTPSLPDDLS DSTSLGTSVI TTCTSVQEQG LKANNSKELS MCFTELTTNI IPGSNKVIKP NSGPSRARPS AALTVLSVLM LKLAL
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 360-464 of human GFRA2 (NP_001486.4).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))
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别名
- GFRA2
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背景
- Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.,GFRA2,GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2,Neuroscience,GFRA2
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分子量
- 36 kDa/39 kDa/51 kDa
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基因ID
- 2675
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UniProt
- O00451
抗原
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