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MTA2 抗体

This anti-MTA2 antibody is a 兔 单克隆 antibody detecting MTA2 in WB, IHC, IF 和 ChIP. Suitable for 人.
产品编号 ABIN1679683
发货至: 中国

Quick Overview for MTA2 抗体 (ABIN1679683)

抗原

See all MTA2 抗体
MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

适用

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宿主

  • 55
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克隆类型

  • 53
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单克隆

标记

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This MTA2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
  • 交叉反应

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human MTA2

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:20 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

    别名

    MTA2

    背景

    This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011],MTA1L1, PID,Chromatin Remodeling,Epigenetics & Nuclear Signaling,MTA2

    分子量

    75 kDa

    基因ID

    9219

    UniProt

    O94776

    途径

    Chromatin Binding
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