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DCLK1 抗体

This anti-DCLK1 antibody is a 兔 单克隆 antibody detecting DCLK1 in WB. Suitable for 人.
产品编号 ABIN1678754
发货至: 中国

Quick Overview for DCLK1 抗体 (ABIN1678754)

抗原

See all DCLK1 抗体
DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

适用

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宿主

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克隆类型

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单克隆

标记

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This DCLK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human DCAMKL1/DCLK1

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))

    别名

    DCLK1

    背景

    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.[provided by RefSeq, Sep 2010],CL1, CLICK1, DCAMKL1, DCDC3A, DCLK,Kinase,Neuroscience,Signal Transduction,DCLK1

    分子量

    82 kDa

    基因ID

    9201

    UniProt

    O15075
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