HTRA2 抗体 (S306A)
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Quick Overview for HTRA2 抗体 (S306A) (ABIN165414)
抗原
See all HTRA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 134-458, S306A
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原理
- Human HTRA2/OMI (S306A) antibody
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纯化方法
- Purified
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免疫原
- Recombinant human HtrA2/Omi (134-458aa) purified from E. coli
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亚型
- IgG1 kappa
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应用备注
- Recommended dilution 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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别名
- HTRA2/OMI
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背景
- HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain, an inhibitor of apoptosis protein (IAP) -binding motif, a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death.
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NCBI登录号
- NP_037379
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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