HDAC1 抗体 (Internal Region)
-
- 抗原 See all HDAC1 抗体
- HDAC1 (Histone Deacetylase 1 (HDAC1))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠, 灵长类
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HDAC1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
- Supplier Product No.
- 600-401-j16
- Supplier
- Rockland
- 原理
- HDAC1 (near C-terminus) Antibody
- 交叉反应 (详细)
- This antibody is specific towards HDAC1.
- 产品特性
- Synonyms: rabbit anti-HDAC-1 antibody, HDAC1, HDAC 1, HD 1 antibody, histone deacetylase 1 antibody, Histone deacetylase-1, HD1 antibody, RPD3L1, reduced potassium dependency yeast homolog like 1 antibody
- 纯化方法
- Anti-HDAC1 was affinity purified from monospecific antiserum by immunoaffinity chromatography.
- 过滤
- Sterile filtered
- 免疫原
-
Immunogen: HDAC1 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human HDAC1.
Immunogen Type: Conjugated Peptide
- Top Product
- Discover our top product HDAC1 Primary Antibody
-
-
- 应用备注
-
Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-HDAC1 antibody is tested for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~62 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.59 mg/mL
- 缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: None - 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 6 months
-
- 抗原
- HDAC1 (Histone Deacetylase 1 (HDAC1))
- 别名
- HDAC1 (HDAC1 产品)
- 背景
- Background: HDAC1 (also known as HD1, histone deacetylase 1, RPD3, RPD3L1) belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Anti-HDAC1 antibodies are ideal for researchers interested in Apoptosis, Breast Cancer, Cancer, Cell Cycle and Replication, Checkpoint signaling, Core ESC Like Genes, Chromatin Research, DNA Double Strand Break Repair, Epigenetics, DNA Repair, Histone Deacetylases, and Stem Cell Marker research.
- 基因ID
- 3065
- NCBI登录号
- NP_004955
- UniProt
- Q13547
- 途径
- Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis
-