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APP 抗体 (N-Term)

Name: APP 抗体 (N-Term)
SKU: ABIN1607880
Availability: OutOfStock

Rockland 600-401-j13 APP 适用: 人, 灵长类 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated

Western Blot of Rabbit Anti-beta Amyloid pyro E11 antibody. (APP 抗体 (N-Term))

1 image

产品编号 ABIN1607880

Supplier Product No.: 600-401-j13

发货至: 中国

Datasheet as PDF

抗原 See all APP 抗体

APP (Amyloid beta (A4) Precursor Protein (APP))
抗原表位
30

27

24

22

17

16

11

8

8

8

7

6

6

5

4

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
243

113

107

12

10

9

9

9

9

8

7

5

4

3

3

1

1

1

1

1
人, 灵长类
宿主
196

83

4

4

2
兔
Compatible Secondaries
克隆类型
216

73
多克隆
标记
155

24

19

18

7

6

4

4

4

4

4

4

4

4

4

4

4

2

2

2

2

2

2

2

2

1
This APP antibody is un-conjugated
应用范围
180

142

76

52

52

44

40

29

27

15

15

6

5

4

3

2

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Supplier Product No.

600-401-j13

Supplier

Rockland

原理

Beta Amyloid pyro E11 Antibody

交叉反应（详细）

This antibody is specific to the N-terminus 11-pyro E start point.

产品特性

Synonyms: rabbit anti-Beta Amyloid pyro E11 Antibody, ß-amyloid pyro E11, Alzheimer disease amyloid protein, Beta amyloid, A-beta, ABPP, APPI

纯化方法

Anti-Beta Amyloid pyro Glu11 was affinity purified from monospecific antiserum by immunoaffinity chromatography.

过滤

Sterile filtered

免疫原

Immunogen: beta Amyloid [Pyro Glu11] affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the N-terminus 11-pyro E start point of human beta Amyloid.
Immunogen Type: Conjugated Peptide

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应用备注

Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-Beta Amyloid pyro Glu11 antibody has been tested by western blot and is useful for ELISA, Western Blot and Immunostaining. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~86.9 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 0.2 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 30 % Glycerol
Preservative: None

储存液

Without preservative

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

6 months
抗原

APP (Amyloid beta (A4) Precursor Protein (APP))

别名

APP (APP 产品)

背景

Background: The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. Beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. Beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. Beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease. Anti-beta Amyloid [Pyro Glu11] antibody is ideal for researchers interested Alzheimer's Research, Cell Cycle and Replication, and Neuroscience research.

基因ID

351

NCBI登录号

NP_000475

UniProt

P05067

途径

Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour