KIT Ligand 抗体
Quick Overview for KIT Ligand 抗体 (ABIN1589938)
抗原
See all KIT Ligand (KITLG) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SCF antibody
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特异性
- Recombinant mouse SCF
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产品特性
- Chromosomal location: 10 D1, 10 57.0 cM
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纯化方法
- Protein A purified
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免疫原
- Recombinant mouse SCF (ABIN1589733)
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亚型
- IgG
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anti-KIT Ligand (KITLG) (AA 151-250) antibody
KITLG 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 26-190) antibodyKITLG 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 244-273) antibodyKITLG 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (Middle Region) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 180-229) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 小鸡, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (Middle Region) antibodyKITLG 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人, 小鼠, 大鼠 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 201-234), (C-Term) antibodyKITLG 适用: 人 WB 宿主: 兔 Polyclonal RB50736 unconjugated
anti-KIT Ligand (KITLG) antibody (Biotin)KITLG 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
- Western Blot: use at 2-5 μg/mL.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- KIT Ligand (KITLG)
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别名
- SCF
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背景
- Kitl, Gb, SF, Sl, Clo, Con, Mgf, SCF, SLF, Kitlg, contrasted,Stem cell factor (SCF), also known as c-kit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I transmembrane glycoprotein. It promotes the survival, differentiation, and mobilization of multiple cell types including myeloid, erythroid, megakaryocytic, lymphoid, germ cell, and melanocyte progenitors. SCF is a primary growth and activation factor for mast cells and eosinophils. Mature mouse SCF consists of a 189 amino acid (aa) extracellular domain (ECD), a 23 aa transmembrane segment, and a 36 aa cytoplasmic tail. The ECD shows both N-linked and O-linked glycosylation. Proteolytic cleavage at two alternate sites in the extracellular juxta-membrane region releases a 25 kDa soluble molecule which is comparable to the only form produced by Steel-dickie mutant mice. An alternately spliced isoform of mouse SCF lacks 28 aa that encompasses the primary proteolytic recognition site. Rat SCF is active on mouse and human cells, but human SCF is only weakly active on mouse cells. Non-covalent dimers of transmembrane or soluble SCF interact with the receptor tyrosine kinase SCF R/ckit to trigger receptor dimerization and signaling. SCF assists in the recovery of cardiac function following myocardial
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基因ID
- 17311
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NCBI登录号
- NM_013598, NP_038626
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UniProt
- P20826
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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