VEGFC 抗体
(1 reference)Quick Overview for VEGFC 抗体 (ABIN1589911)
抗原
See all VEGFC 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- VEGF-C antibody
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特异性
- Recombinant rat VEGF-C
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产品特性
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Chromosomal location: 16p11
Produced from sera of rabbits immunized with highly pure recombinant rat dNdC-VEGF-C. -
纯化方法
- Anti-rat VEGF-C IgG was purified by affinity chromatography with immobilized Protein A.
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免疫原
- Recombinant rat VEGF-C (ABIN1589785)
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亚型
- IgG
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anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 108-223) antibody
VEGFC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 321-415) antibodyVEGFC 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 20-49) antibodyVEGFC 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 20-49), (N-Term) antibodyVEGFC 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB11713 unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 108-223) antibodyVEGFC 适用: 大鼠 WB 宿主: 小鼠 Monoclonal D3 unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 112-227) antibodyVEGFC 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 1-290) antibodyVEGFC 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 47-413) antibodyVEGFC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) (AA 27-57), (N-Term) antibodyVEGFC 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Vascular Endothelial Growth Factor C (VEGFC) antibodyVEGFC 适用: 人, 小鼠, 大鼠 WB 宿主: 小鼠 Monoclonal 7C4 unconjugated
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应用备注
- Western Blot: Use 2-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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: "Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis." in: PLoS ONE, Vol. 9, Issue 9, pp. e106976, (2014) (PubMed).
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: "Bone marrow-derived mesenchymal stem cells drive lymphangiogenesis." in: PLoS ONE, Vol. 9, Issue 9, pp. e106976, (2014) (PubMed).
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- VEGFC (Vascular Endothelial Growth Factor C (VEGFC))
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别名
- VEGF-C
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背景
- Vascular endothelial growth factor C, Vegfc,VEGF-C, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-C is expressed in various tissues, but is not produced in peripheral blood lymphocytes. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-C may play a role in the formation of the venous and lymphatic vascular systems. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant, fully processed rat VEGF-C is a 16-18 kDa non-disulfide linked homodimeric protein consisting of two 116 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
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基因ID
- 114111
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NCBI登录号
- NM_053653, NP_446105
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UniProt
- O35757
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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