CEACAM1 抗体 (deltaN-Term)
Quick Overview for CEACAM1 抗体 (deltaN-Term) (ABIN1589889)
抗原
See all CEACAM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- deltaN-Term
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原理
- CEACAM-1 (dN) antibody
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特异性
- Recombinant human sCEA-1 (ΔN)
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产品特性
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Chromosomal location: 19q13.2
Produced from sera of rabbits immunized with highly pure recombinant human soluble CEACAM-1 (ΔN) (Carcinoembryonic antigen-related cell adhesion molecule-1, SwissProt: #P13688) as the immunizing antigen. -
纯化方法
- Anti-human soluble CEACAM-1 was purified by affinity chromatography with immobilized Protein A.
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免疫原
- Recombinant human sCEA-1 (deltaN)
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亚型
- IgG
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) antibody
CEACAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) antibodyCEACAM1 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 65-201) antibodyCEACAM1 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 7B9G3 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 300-430) antibodyCEACAM1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) antibodyCEACAM1 适用: 人 FACS, IHC (fro), cELISA 宿主: 小鼠 Monoclonal GM-8G5 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 35-143) antibodyCEACAM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 36-145) antibodyCEACAM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 1-468) antibodyCEACAM1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) (AA 65-201) antibodyCEACAM1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4F3B2 unconjugated
anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) antibodyCEACAM1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C4 unconjugated
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应用备注
- Western Blot: Use 2-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))
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别名
- CEACAM-1
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背景
- CEACAM1, BGP, BGP1, BGPI, CD66a,Carcinoembryonic antigen (CEA)-related cell adhesion molecule 1 (CEACAM1, also BGP) is a 160 kDa member of the CEACAM branch of the CEA gene family of the immunoglobulin superfamily (1-3). It is one of seven human CEACAM subfamily genes that are essentially divided equally between type I trans-membrane proteins (CEACAM1, 3-4) and GPI-linked molecules (CEACAM5-8). There is no CEACAM2 in human. The gene for human CEACAM1 codes for a 526 amino acid (aa) type I transmembrane protein that contains a 34 aa signal sequence, a 394 aa extracellular domain (ECD), a 24 aa transmembrane segment, and a 74aa cytoplasmic region (4, 5). The ECD contains one N-terminal V-type followed by three C2-type Ig-like domains. It shows considerable glycosylation (1). The cytoplasmic region shows one ITIM motif and a calmodulin binding site (1-3). There are three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic region. All ten alternate splice forms contain the V-type Ig-like domain (aa's 35-142). The three soluble forms also contain the first two C2-type Ig like domains (aa's 145 317), with differences coming in the third C2-type Ig- like domain (6). The seven transmembrane isoforms are highly divergent. Full-length mouse and rat CEACAM1 are approximately 57 % aa identical to human CEACAM1, in the V-type Ig-like domain, they are 58 % and 56 % aa identical, respectively. The full-length molecule is found on neutrophils, bile duct epithelium, activated NK cells, colonic columnar epithelium and endothelium.
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基因ID
- 634
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NCBI登录号
- NM_001205344, NP_001192273
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UniProt
- P13688
抗原
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