VEGFR2/CD309 抗体 (Soluble)
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Quick Overview for VEGFR2/CD309 抗体 (Soluble) (ABIN1589863)
抗原
See all VEGFR2/CD309 (VEGFR2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Soluble
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原理
- Rabbit Anti-Mouse VEGFR-2/Flk-1 (Peptide), soluble Polyclonal Antibody
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特异性
- Peptide: GMEASLGDRIAMP
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产品特性
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Chromosomal location: 5 C3.3, 5 42.0 cM
Produced from sera of rabbits immunised with a peptide of the C-terminal end of native mouse soluble VEGFR-2/Flk-1 (GMEASLGDRIAMP). -
纯化方法
- Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A.
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免疫原
- peptide: GMEASLGDRIAMP
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亚型
- IgG
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应用备注
- Western Blot: use at 1-5 μg/mL.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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别名
- VEGFR-2/Flk-1
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背景
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Synonyms: soluble vascular endothelial growth factor receptor-2 , soluble Kdr, soluble Ly73, soluble Flk-1, sVEGFR2, sVEGF receptor 2, soluble kinase insert domain protein receptor
Description: The antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle, other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C, ligand binding plays a key role in vascular development and vascular permeability.
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基因ID
- 16542
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UniProt
- P35918
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途径
- RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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