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FLT4 抗体

This anti-FLT4 antibody is a 大鼠 单克隆 antibody detecting FLT4 in WB. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1589862
发货至: 中国

Quick Overview for FLT4 抗体 (ABIN1589862)

抗原

See all FLT4 抗体
FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

适用

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  • 12
小鼠

宿主

  • 78
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  • 7
  • 2
  • 1
大鼠

克隆类型

  • 79
  • 35
单克隆

标记

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  • 4
  • 1
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  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FLT4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

7A3
  • 特异性

    Recombinant mouse soluble FLT-4

    产品特性

    Chromosomal location: 11 A5-B1, 11 25.0 cM
    The hybridoma was generated after fusion with cells from rat immunized with purified, insect cell-derived recombinant mouse soluble FLT-4 (120 kDa) as the immunizing antigen.

    纯化方法

    Rat IgG1 antibody from hybridomas was purified from cell culture supernatant by Protein G chromatography.
  • 应用备注

    Western Blot: use 1-5 µg/mL.

    说明

    Monoclonal Antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS

    注意事项

    Centrifuge vial prior to opening.

    储存条件

    -20 °C

    储存方法

    The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

    有效期

    6 months
  • Tempfer, Kaser-Eichberger, Korntner, Lehner, Kunkel, Traweger, Trost, Strohmaier, Bogner, Runge, Bruckner, Krefft, Heindl, Reitsamer, Schrödl: "Presence of lymphatics in a rat tendon lesion model." in: Histochemistry and cell biology, Vol. 143, Issue 4, pp. 411-9, (2015) (PubMed).

  • 抗原

    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

    别名

    VEGFR-3/FLT-4

    背景

    VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis.
    Synonyms: vascular endothelial growth factor receptor-3, Flt4, Chy, Flt-4, VEGFR3, VEGFR-3,

    NCBI登录号

    NP_032055, NM_008029

    UniProt

    P35917

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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