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FLT4 抗体

FLT4 适用: 人 WB, ELISA, IP, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1589828
发货至: 中国
  • 抗原 See all FLT4 抗体
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    适用
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    宿主
    • 66
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    克隆类型
    • 67
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    多克隆
    标记
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    This FLT4 antibody is un-conjugated
    应用范围
    • 52
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    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recombinant human sFLT-4 (D1-7)
    产品特性
    Chromosomal location: 5q35.3
    Produced from sera of rabbits immunised with highly pure recombinant human soluble VEGFR-3/FLT-4 (D1-D7).
    纯化方法
    Anti-human VEGFR-3/FLT-4 was purified by antigen-affinity chromatography with immobilised soluble VEGFR-3/FLT-4.
    亚型
    IgG
    Top Product
    Discover our top product FLT4 Primary Antibody
  • 应用备注
    Western Blot: use 1-5 µg/mL
    说明

    Rabbit IG Polyclonal Antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS
    注意事项
    Centrifuge vial prior to opening.
    储存条件
    -20 °C
    储存方法
    The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
    有效期
    6 months
  • Liu, Li, Zhang, Rao, Liang, Liu: "The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia." in: Placenta, Vol. 36, Issue 3, pp. 279-86, (2015) (PubMed).

  • 抗原
    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
    别名
    VEGFR-3/FLT-4 (FLT4 产品)
    别名
    FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody
    背景
    Receptor tyrosine Kinase VEGFR-3, also known as FLT4, together with VEGFR1 (FIT1) and VEGFR2 (KDR/Flk-1), are the receptors for vascular endothelial growth factors (VEGF). The VEGFR family belongs to the class II subfamily of receptor tyrosine kinases (RTKs), containing a large extracellular region which is composed of seven Ig-like domains (D1–D7), a single transmembrane (TM) helix and cytoplasmic region with a tyrosine kinase activity. In VEGFR-3, the fifth Ig homology domain is proteolytically cleaved which results in polypeptides remain linked by two disulfide bonds. VEGFR-3 is widely expressed on all endothelia cells in early embryogenesis, while, in adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGF-C and VEGF-D activation of VEGFR-3 plays an important role in the formation of the lymphatic vessel system.
    Synonyms: vascular endothelial growth factor receptor-3, FLT4, PCL, LMPH1A, VEGFR3, fms-related tyrosine kinase 4
    NCBI登录号
    NP_002011, NM_002020
    UniProt
    P35916
    途径
    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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