FLT4 抗体
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北京 101111
Quick Overview for FLT4 抗体 (ABIN1589828)
抗原
See all FLT4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- VEGFR-3/FLT-4 antibody
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特异性
- Recombinant human sFLT-4 (D1-7)
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产品特性
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Chromosomal location: 5q35.3
Produced from sera of rabbits immunised with highly pure recombinant human soluble VEGFR-3/FLT-4 (D1-D7). -
纯化方法
- Anti-human VEGFR-3/FLT-4 was purified by antigen-affinity chromatography with immobilised soluble VEGFR-3/FLT-4.
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免疫原
- Recombinant human sFLT-4 (D1-7) (ABIN1589554 and ABIN1589553)
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亚型
- IgG
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anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibody
FLT4 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 25-259) antibodyFLT4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 1-439) antibodyFLT4 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 818CT12-1-1 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibodyFLT4 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 818CT12-1-1 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 901-1000) antibodyFLT4 适用: 人, 小鼠, Cow ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibodyFLT4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 34-133) antibodyFLT4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B5 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibodyFLT4 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal 8C1 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibodyFLT4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 1112-1329) antibodyFLT4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western Blot: Use 1-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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: "The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia." in: Placenta, Vol. 36, Issue 3, pp. 279-86, (2015) (PubMed).
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: "The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia." in: Placenta, Vol. 36, Issue 3, pp. 279-86, (2015) (PubMed).
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- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
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别名
- VEGFR-3/FLT-4
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背景
- Vascular endothelial growth factor receptor-3, FLT4, PCL, LMPH1A, VEGFR3, fms-related tyrosine kinase 4,Receptor tyrosine Kinase VEGFR-3, also known as FLT4, together with VEGFR1 (FIT1) and VEGFR2 (KDR/Flk-1), are the receptors for vascular endothelial growth factors (VEGF). The VEGFR family belongs to the class II subfamily of receptor tyrosine kinases (RTKs), containing a large extracellular region which is composed of seven Ig-like domains (D1-D7), a single transmembrane (TM) helix and cytoplasmic region with a tyrosine kinase activity. In VEGFR-3, the fifth Ig homology domain is proteolytically cleaved which results in polypeptides remain linked by two disulfide bonds. VEGFR-3 is widely expressed on all endothelia cells in early embryogenesis, while, in adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGF-C and VEGF-D activation of VEGFR-3 plays an important role in the formation of the lymphatic vessel system.
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基因ID
- 2324
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NCBI登录号
- NM_002020, NP_002011
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UniProt
- P35916
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
抗原
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