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LGALS1/Galectin 1 抗体

This anti-LGALS1/Galectin 1 antibody is a 兔 多克隆 antibody detecting LGALS1/Galectin 1 in WB. Suitable for 人.
产品编号 ABIN1589812
发货至: 中国

Quick Overview for LGALS1/Galectin 1 抗体 (ABIN1589812)

抗原

See all LGALS1/Galectin 1 (LGALS1) 抗体
LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

适用

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克隆类型

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多克隆

标记

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This LGALS1/Galectin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    Galectin-1 antibody

    特异性

    Recombinant human Galectin-1

    产品特性

    Chromosomal location: 22q13.1

    纯化方法

    Protein A purified

    免疫原

    Recombinant human Galectin-1

    亚型

    IgG
  • 应用备注

    Western Blot: Use 1-5 μg/mL

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    3 mM PBS, pH 7.2

    注意事项

    Centrifuge vial prior to opening.

    储存条件

    4 °C,-20 °C

    储存方法

    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

    有效期

    24 months
  • 抗原

    LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

    别名

    Galectin-1

    背景

    LGALS1, GBP, GAL1,Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88 % amino acid sequence similarity.

    基因ID

    3956

    NCBI登录号

    NM_002305, NP_002296

    UniProt

    P09382

    途径

    Carbohydrate Homeostasis
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