LGALS1/Galectin 1 抗体
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北京 101111
Quick Overview for LGALS1/Galectin 1 抗体 (ABIN1589812)
抗原
See all LGALS1/Galectin 1 (LGALS1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Galectin-1 antibody
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特异性
- Recombinant human Galectin-1
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产品特性
- Chromosomal location: 22q13.1
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纯化方法
- Protein A purified
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免疫原
- Recombinant human Galectin-1
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亚型
- IgG
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anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibody
LGALS1 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1E8-1B2 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: Cow WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 12-108) antibodyLGALS1 适用: 人 WB, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal GAL1-1831 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H11C5 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) antibodyKD Validated LGALS1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6025 unconjugated Recombinant Antibody
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 12-108) antibodyLGALS1 适用: 人 IHC, ELISA, Coat, StM 宿主: 兔 Monoclonal GAL1-2499R unconjugated Recombinant Antibody
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) antibodyKO Validated LGALS1 适用: 人 WB, IP, ICC, IF, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) (AA 1-135) antibodyLGALS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 1 (LGALS1) antibodyKD Validated LGALS1 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB6280 unconjugated Recombinant Antibody
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应用备注
- Western Blot: Use 1-5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- 3 mM PBS, pH 7.2
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
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有效期
- 24 months
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- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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别名
- Galectin-1
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背景
- LGALS1, GBP, GAL1,Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88 % amino acid sequence similarity.
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基因ID
- 3956
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NCBI登录号
- NM_002305, NP_002296
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UniProt
- P09382
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途径
- Carbohydrate Homeostasis
抗原
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