LYVE1 抗体 (Biotin)
Quick Overview for LYVE1 抗体 (Biotin) (ABIN1589714)
抗原
See all LYVE1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recombinant mouse soluble LYVE-1
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产品特性
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Chromosomal location: 7, 7F2
Produced from sera of rabbits immunised with highly pure recombinant mouse soluble LYVE-1 produced in insect cells. The recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis). LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE 1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves. -
纯化方法
- The antibody was purified via an antigen-affinity column and then biotinylated using a standard protocol.
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亚型
- IgG
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anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 231-318) antibody
LYVE1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 46-77), (N-Term) antibodyLYVE1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2930 unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-238) antibodyLYVE1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 24-228) antibodyLYVE1 适用: 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-238) antibodyLYVE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) antibodyLYVE1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) antibodyLYVE1 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (N-Term) antibodyLYVE1 适用: 人, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 24-228) antibodyLYVE1 适用: 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- FACS: use 3-10 µg/mL
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说明
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Rabbit IG Polyclonal Antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, BSA (50x), 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Centrifuge vial prior to opening.
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储存条件
- -20 °C
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储存方法
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
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有效期
- 6 months
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- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
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别名
- Lyve-1
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背景
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LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Synonyms: Lyve1, Xlkd1, Lyve-1, Crsbp-1, 1200012G08Rik -
NCBI登录号
- NP_444477, NM_053247
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UniProt
- Q8BHC0
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途径
- Glycosaminoglycan Metabolic Process
抗原
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