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LYVE1 抗体 (Biotin)

This Biotin-conjugated 兔 多克隆 anti-LYVE1 antibody specifically detects LYVE1 in WB 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN1589713
发货至: 中国
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Quick Overview for LYVE1 抗体 (Biotin) (ABIN1589713)

抗原

See all LYVE1 抗体
LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

适用

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宿主

  • 95
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克隆类型

  • 83
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多克隆

标记

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This LYVE1 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 特异性

    Recombinant human sLYVE-1

    产品特性

    Chromosomal location: 11p15
    Produced from sera of rabbits immunized with highly pure recombinant human soluble LYVE-1 produced in insect cells. The recombinant soluble LYVE-1 consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis).

    纯化方法

    The antibody was purified via an antigen-affinity column and then biotinylated using a standard protocol.

    亚型

    IgG
  • 应用备注

    FACS: use 3-10 µg/mL

    说明

    Rabbit IG Polyclonal Antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, BSA (50x), 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Centrifuge vial prior to opening.

    储存条件

    -20 °C

    储存方法

    The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.

    有效期

    6 months
  • 抗原

    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

    别名

    Lyve-1

    背景

    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule co-localizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
    Synonyms: LYVE1, HAR, XLKD1, LYVE-1, CRSBP-1

    NCBI登录号

    NP_006682, NM_006691

    UniProt

    Q9Y5Y7

    途径

    Glycosaminoglycan Metabolic Process
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