(1 reference)-
- 抗原 See all TEK 抗体
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TEK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 原理
- TIE-2 antibody
- 特异性
- Recombinant human soluble extracellular TIE-2
- 产品特性
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Chromosomal location: 9p21
The monoclonal antibody was produced with the help of BALB/c mice using recombinant human soluble extracellular TIE-2 as the immunizing antigen. - 纯化方法
- Mouse IgG1 antibody (#tek16) from hybridomas was purified from cell culture supernatant by Protein G chromatography.
- 免疫原
- Recombinant human soluble extracellular TIE-2
- 克隆位点
- Tek16
- 亚型
- IgG1
- Top Product
- Discover our top product TEK Primary Antibody
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anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 66-185) antibody
TEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 571-748) antibodyTEK 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F5B9 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789) antibodyTEK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F8 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 401-550) antibodyTEK 适用: 人, 小鼠, 大鼠, Cow ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 286-465) antibodyTEK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5G6 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (C-Term) antibodyTEK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 500-750) antibodyTEK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789), (C-Term) antibodyTEK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01525-01526 unconjugated
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- 应用备注
- ELISA: Use at 1-2 μg/mL. Western blotting: Use at 2-5 μg/mL. FACS analysis: Use at 2-5 μg/mL.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- PBS
- 注意事项
- Centrifuge vial prior to opening.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
- 有效期
- 24 months
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: "Human liver sinusoidal endothelial cells but not hepatocytes contain factor VIII." in: Journal of thrombosis and haemostasis : JTH, Vol. 12, Issue 1, pp. 36-42, (2014) (PubMed).
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: "Human liver sinusoidal endothelial cells but not hepatocytes contain factor VIII." in: Journal of thrombosis and haemostasis : JTH, Vol. 12, Issue 1, pp. 36-42, (2014) (PubMed).
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- 抗原
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
- 别名
- TIE-2 (TEK 产品)
- 背景
- TEK, TIE2, VMCM, TIE-2, VMCM1, CD202B,Tie-1/Tie and Tie-2/Tek are receptor tyrosine kinases with unique structural characteristics including two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains, followed by three fibronectin type III-like repeats in the extracellular region, and a split tyrosine kinase domain in the cytoplasmic region. Tie-2 is involved in vascular stabilization and remodeling. Although less well understood, Tie-1 may also act as an ANG receptor, possibly in complex with Tie-2. Human Tie-2 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Tie-2 is a receptor for the angiopoietin (ANG) family: ANG-1, ANG-2, and ANG-3 (mouse)/-4 (human). Ang-2 has been reported to act as an antagonist for Ang-1. Mice engineered to overexpress Ang-2 or to lack Ang-1 or Tie-2 display similar angiogenesis defects.
- 基因ID
- 7010
- NCBI登录号
- NM_000459, NP_000450
- UniProt
- Q02763
- 途径
- RTK signaling, Growth Factor Binding
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