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TIE1 抗体

TIE1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6F12 unconjugated
产品编号 ABIN1589693
发货至: 中国
  • 抗原 See all TIE1 抗体
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    适用
    • 87
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    宿主
    • 69
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    小鼠
    克隆类型
    • 70
    • 20
    单克隆
    标记
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    This TIE1 antibody is un-conjugated
    应用范围
    • 68
    • 39
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    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    TIE-1 antibody
    特异性
    Recombinant human soluble TIE-2
    交叉反应 (详细)
    The monoclonal antibody will detect native human TIE-1 in ELISA experiments and on the surface of different human cell types. The antibody can be used for ELISA experiments and Western blotting.
    产品特性
    Chromosomal location: 1p34-p33
    The monoclonal antibody was produced with the help of BALB/c mice using recombinant human soluble extracellular TIE-1 as the immunizing antigen.
    纯化方法
    Mouse IgG1 antibody (#6F12) from hybridomas was purified from cell culture supernatant by Protein G chromatography.
    免疫原
    Recombinant human soluble TIE-1
    克隆位点
    6F12
    亚型
    IgG1
    Top Product
    Discover our top product TIE1 Primary Antibody
  • 应用备注
    ELISA: Use at 1-15 μg/mL, Western blotting: Use at 1-2 μg/mL, FACS analysis and cell sorting: Test under progress.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS
    注意事项
    Centrifuge vial prior to opening.
    储存条件
    4 °C,-20 °C
    储存方法
    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
    有效期
    24 months
  • 抗原
    TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
    别名
    TIE-1 (TIE1 产品)
    背景
    TIE1, TIE, JTK14,Tie-1/Tie and Tie-2/Tek are receptor tyrosine kinases with unique structural characteristics including two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains, followed by three fibronectin type III-like repeats in the extracellular region, and a split tyrosine kinase domain in the cytoplasmic region. Tie-2 is a receptor for the angiopoietin (ANG) family: ANG-1, ANG-2, and ANG-3 (mouse)/-4 (human). It is involved in vascular stabilization and remodeling. Although less well understood, Tie-1 may also act as an ANG receptor, possibly in complex with Tie-2.
    基因ID
    7075
    NCBI登录号
    NM_005424, NP_005415
    UniProt
    P35590
    途径
    RTK signaling
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