TIE1 抗体 (Biotin)
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北京 101111
Quick Overview for TIE1 抗体 (Biotin) (ABIN155170)
抗原
See all TIE1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This unconjugated monoclonal antibody will detect native TIE-1 in ELISA experiments and on the surface of different cell types.
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纯化方法
- Protein G Chromatography.
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免疫原
- Recombinant human soluble TIE-1 protein.
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亚型
- IgG1
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anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 385-607) antibody
TIE1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 8D12D2 unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 385-607) antibodyTIE1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8D12B10 unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 435-609) antibodyTIE1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 701-898) antibodyTIE1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 701-898) antibodyTIE1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 217-328) antibodyTIE1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) antibodyTIE1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB725 unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 536-643) antibodyTIE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) antibodyTIE1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1) (AA 361-389) antibodyTIE1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1-15 μg/mL. Western blot: 1-2 μg/mL. FACS: 2-5 μg/mL. Cell sorting: 2-5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide, BSA (50X)
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- This product is photosensitive and should be protected from light
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted Prior to and After reconstitution at 2-8 °C. DO NOT FREEZE!
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- TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))
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别名
- TIE1
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背景
- The soluble receptor protein consists of the full extracellular domain (Met1-Glu749). The recombinant mature TIE-1/Fc is a disulfide-linked homodimeric protein. Human TIE-1/Fc monomer has a calculated molecular mass of approximately 105 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 125 kDa protein in SDS-PAGE under reducing conditions.TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-1 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18 residue putative signal peptide, a 727 residue extracellular domain and a 354 residue cytoplasmic domain. Whereas two ligands have been described for TIE-2 [angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2)], so far no ligand was found for TIE-1.Synonyms: TIE, Tie-1, Tyrosine-protein kinase receptor Tie-1
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基因ID
- 7075
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NCBI登录号
- NP_005415
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UniProt
- P35590
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途径
- RTK signaling
抗原
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