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TEK 抗体 (Extracellular Domain) (Biotin)

This 小鼠 单克隆 antibody specifically detects TEK in WB, FACS 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN155164
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for TEK 抗体 (Extracellular Domain) (Biotin) (ABIN155164)

抗原

See all TEK 抗体
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

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宿主

  • 119
  • 24
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  • 1
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小鼠

克隆类型

  • 125
  • 30
单克隆

标记

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This TEK antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

克隆位点

Cl-9
  • 抗原表位

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    Extracellular Domain

    特异性

    The unconjugated antibody will detect native TIE-2/tek.

    纯化方法

    Protein G chromatography

    免疫原

    Recombinant human soluble extracellular TIE-2

    亚型

    IgG1
  • 应用备注

    ELISA. Western Blot. FACS analysis and cell sorting: 2-5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Reconstitute to a concentration of 50 μg/mL with sterile PBS solution containing 0.1 % BSA

    缓冲液

    0.1 M Tris-Cl, 0.1 M NaCl, 0.02 % NaN3, pH 7.4 containing 50x BSA as stabilizer

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    别名

    CD202b / TEK

    背景

    TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

    基因ID

    7010

    NCBI登录号

    NP_000450

    UniProt

    Q02763

    途径

    RTK signaling, Growth Factor Binding
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