ELK1 抗体 (pSer383)
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北京 101111
Quick Overview for ELK1 抗体 (pSer383) (ABIN155121)
抗原
See all ELK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer383
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特异性
- The antibody detects 62 kDa phosphorylated Elk-1 (Ser383).
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纯化方法
- Affinity purified
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免疫原
- Synthetic peptide surrounding amino acid 383 of human Elk-1.
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应用备注
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))
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别名
- ELK1
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背景
- Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk-1 is a good substrate for MAP kinase. The kinetics of Elk-1 phosphorylation and activation correlate with MAP kinase activity. Other studies have shown that Elk-1 (Ser383) is also a target of the stress-activated kinase SAPK/JNK.Synonyms: ETS domain-containing protein Elk-1, Elk-1
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基因ID
- 2002
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NCBI登录号
- NP_001107595
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UniProt
- P19419
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
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