Vitamin D Receptor 抗体
Quick Overview for Vitamin D Receptor 抗体 (ABIN1540015)
抗原
See all Vitamin D Receptor (VDR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This VDR antibody is generated from rabbits immunized with a recombinant protein of human VDR.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- VDR Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- Vitamin D Receptor (VDR)
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别名
- VDR
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物质类
- Chemical
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背景
- This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
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分子量
- 48289
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基因ID
- 7421
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NCBI登录号
- NP_000367, NP_001017535, NP_001017536
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UniProt
- P11473
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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