Androgen Receptor 抗体
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- 抗原 See all Androgen Receptor (AR) 抗体
- Androgen Receptor (AR)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Androgen Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- Purified His-tagged Androgen Receptor Protein(Fragment) was used to produced this monoclonal antibody.
- 克隆位点
- 549CT16-1-4
- 亚型
- IgA
- Top Product
- Discover our top product AR Primary Antibody
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- 应用备注
- WB: 1:100~250
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Androgen Receptor Protein can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- 有效期
- 6 months
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- 抗原
- Androgen Receptor (AR)
- 别名
- Androgen Receptor (AR 产品)
- 别名
- AIS antibody, DHTR antibody, HUMARA antibody, HYSP1 antibody, KD antibody, NR3C4 antibody, SBMA antibody, SMAX1 antibody, TFM antibody, AW320017 antibody, Tfm antibody, Andr antibody, AR antibody, androgen receptor antibody, AR antibody, Ar antibody, ar antibody
- 背景
- The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq].
- 分子量
- 99188
- 基因ID
- 367
- NCBI登录号
- NP_000035, NP_001011645
- UniProt
- P10275
- 途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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