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Caspase 3 抗体 (pSer12)

This anti-Caspase 3 antibody is a 兔 多克隆 antibody detecting Caspase 3 in DB. Suitable for 小鼠.
产品编号 ABIN1539692
发货至: 中国

Quick Overview for Caspase 3 抗体 (pSer12) (ABIN1539692)

抗原

See all Caspase 3 (CASP3) 抗体
Caspase 3 (CASP3)

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Caspase 3 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB39711
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    pSer12

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This mouse CASP3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S12 of mouse CASP3.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Phospho-mouse CASP3-S12 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    Caspase 3 (CASP3)

    别名

    CASP3

    背景

    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq].

    分子量

    31475

    基因ID

    12367

    NCBI登录号

    NP_033940

    UniProt

    P70677

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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