RNASEL 抗体 (N-Term)
Quick Overview for RNASEL 抗体 (N-Term) (ABIN1539054)
抗原
See all RNASEL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 140-167, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Rnasel antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-167 amino acids from the N-terminal region of mouse Rnasel.
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亚型
- Ig Fraction
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anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 472-741) antibody
RNASEL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) antibodyRNASEL 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 358-583) antibodyRNASEL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 330-741) antibodyRNASEL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 619-728) antibodyRNASEL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) (AA 619-728) antibodyRNASEL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL) antibodyRNASEL 适用: 人, 猴 WB, ELISA 宿主: 小鼠 Monoclonal (2E9) unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Mouse Rnasel Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
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别名
- Rnasel
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背景
- Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis. Therefore, activation of RNASEL could lead to elimination of virus infected cells under some circumstances. Might play a central role in the regulation of mRNA turnover (By similarity).
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分子量
- 83275
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基因ID
- 24014
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NCBI登录号
- NP_036012
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UniProt
- Q05921
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途径
- Hepatitis C
抗原
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