This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This NGFRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human NGFRAP1.
NGFRAP1 may be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.