ULBP2 抗体 (AA 88-116)
Quick Overview for ULBP2 抗体 (AA 88-116) (ABIN1538674)
抗原
See all ULBP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 88-116
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ULBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human ULBP2.
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亚型
- Ig Fraction
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anti-UL16 Binding Protein 2 (ULBP2) (AA 26-216) antibody
ULBP2 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1F12C2 unconjugated
anti-UL16 Binding Protein 2 (ULBP2) (AA 1-246) antibodyULBP2 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-UL16 Binding Protein 2 (ULBP2) (AA 26-216) antibodyULBP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-UL16 Binding Protein 2 (ULBP2) (AA 26-246) antibodyULBP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- ULBP2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- ULBP2 (UL16 Binding Protein 2 (ULBP2))
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别名
- ULBP2
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背景
- Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
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分子量
- 27368
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基因ID
- 80328
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NCBI登录号
- NP_079493
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UniProt
- Q9BZM5
抗原
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