OPTN 抗体 (AA 71-96)
Our Local Distributor
北京 101111
Quick Overview for OPTN 抗体 (AA 71-96) (ABIN1538582)
抗原
See all OPTN 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 71-96
-
预测反应
- Rat
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This OPTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-96 amino acids from the Central region of human OPTN.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- OPTN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
-
有效期
- 6 months
-
-
- OPTN (Optineurin (OPTN))
-
别名
- OPTN
-
背景
- This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
-
分子量
- 65922
-
基因ID
- 10133
-
NCBI登录号
- NP_001008212, NP_001008213, NP_001008214, NP_068815
-
UniProt
- Q96CV9
-
途径
- M Phase
抗原
-