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OPTN 抗体 (AA 71-96)

This anti-OPTN antibody is a 兔 多克隆 antibody detecting OPTN in WB. Suitable for 人.
产品编号 ABIN1538582
发货至: 中国

Quick Overview for OPTN 抗体 (AA 71-96) (ABIN1538582)

抗原

See all OPTN 抗体
OPTN (Optineurin (OPTN))

适用

  • 54
  • 34
  • 16
  • 7
  • 6
  • 5
  • 5
  • 5
  • 2
  • 2
  • 1

宿主

  • 54
  • 5

克隆类型

  • 53
  • 6
多克隆

标记

  • 33
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OPTN antibody is un-conjugated

应用范围

  • 50
  • 14
  • 13
  • 13
  • 13
  • 12
  • 8
  • 7
  • 5
  • 3
  • 2
Western Blotting (WB)

克隆位点

RB21453
  • 抗原表位

    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 71-96

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This OPTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-96 amino acids from the Central region of human OPTN.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    OPTN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    OPTN (Optineurin (OPTN))

    别名

    OPTN

    背景

    This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

    分子量

    65922

    基因ID

    10133

    NCBI登录号

    NP_001008212, NP_001008213, NP_001008214, NP_068815

    UniProt

    Q96CV9

    途径

    M Phase
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