HLA-C 抗体 (AA 66-93)
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Quick Overview for HLA-C 抗体 (AA 66-93) (ABIN1538555)
抗原
See all HLA-C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 66-93
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HLA-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the Central region of human HLA-C.
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亚型
- Ig Fraction
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anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 25-308) antibody
HLA-C 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 62-306) antibodyHLA-C 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 38-62), (C-Term) antibodyHLA-C 适用: 人 WB, IHC, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) antibodyKO Validated HLA-C 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB8545 unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) antibodyHLA-C 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 200-306) antibodyHLA-C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 1-366) antibodyHLA-C 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) antibodyHLA-C 适用: 人, Non-Human Primate IP, FACS 宿主: 小鼠 Monoclonal DT-9 unconjugated
anti-Major Histocompatibility Complex Class I C (HLA-C) antibody (PE)HLA-C 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal DT-9 PE
anti-Major Histocompatibility Complex Class I C (HLA-C) (AA 25-308) antibody (Biotin)HLA-C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal Biotin
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- HLA-C Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- HLA-C (Major Histocompatibility Complex Class I C (HLA-C))
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别名
- HLA-C
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背景
- HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described
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分子量
- 40649
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基因ID
- 3107
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NCBI登录号
- NP_002108
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UniProt
- P10321
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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