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TFEB 抗体 (AA 271-300)

This 兔 多克隆 antibody specifically detects TFEB in WB. It exhibits reactivity toward 人.
产品编号 ABIN1538221
发货至: 中国
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Quick Overview for TFEB 抗体 (AA 271-300) (ABIN1538221)

抗原

See all TFEB 抗体
TFEB (Transcription Factor EB (TFEB))

适用

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宿主

  • 70
  • 7
  • 1

克隆类型

  • 59
  • 18
多克隆

标记

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This TFEB antibody is un-conjugated

应用范围

  • 72
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  • 9
  • 4
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Western Blotting (WB)

克隆位点

RB39331
  • 抗原表位

    • 16
    • 9
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    AA 271-300

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TFEB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human TFEB.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    TFEB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    TFEB (Transcription Factor EB (TFEB))

    别名

    TFEB

    背景

    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.

    分子量

    52865

    基因ID

    7942

    NCBI登录号

    NP_001161299, NP_001258872, NP_001258873, NP_001258874, NP_009093

    UniProt

    P19484
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