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TDP1 抗体 (AA 212-239)

This anti-TDP1 antibody is a 兔 多克隆 antibody detecting TDP1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN1538086
发货至: 中国

Quick Overview for TDP1 抗体 (AA 212-239) (ABIN1538086)

抗原

See all TDP1 抗体
TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

适用

  • 36
  • 16
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 32
  • 6
  • 1

克隆类型

  • 35
  • 4
多克隆

标记

  • 30
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This TDP1 antibody is un-conjugated

应用范围

  • 32
  • 17
  • 12
  • 11
  • 7
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB36293
  • 抗原表位

    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 212-239

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TDP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-239 amino acids from the Central region of human TDP1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    TDP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))

    别名

    TDP1

    背景

    The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

    分子量

    68420

    基因ID

    55775

    NCBI登录号

    NP_001008744, NP_060789

    UniProt

    Q9NUW8
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