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WEE1 抗体 (AA 202-230)

This 兔 多克隆 anti-WEE1 antibody (Clone RB39511) specifically detects WEE1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1538059
发货至: 中国
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Quick Overview for WEE1 抗体 (AA 202-230) (ABIN1538059)

抗原

See all WEE1 抗体
WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

适用

  • 86
  • 49
  • 36
  • 2

宿主

  • 96
  • 5
  • 2

克隆类型

  • 101
  • 2
多克隆

标记

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  • 2
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  • 2
  • 2
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  • 2
  • 2
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  • 1
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This WEE1 antibody is un-conjugated

应用范围

  • 81
  • 48
  • 28
  • 28
  • 20
  • 16
  • 8
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
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Western Blotting (WB)

克隆位点

RB39511
  • 抗原表位

    • 20
    • 15
    • 11
    • 9
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
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    • 1
    AA 202-230

    预测反应

    Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Wee1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of mouse Wee1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Mouse Wee1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

    别名

    Wee1

    背景

    Wee1 may act as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur (By similarity).

    分子量

    71578

    基因ID

    22390

    NCBI登录号

    NP_033542

    UniProt

    P47810

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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