RRM2B 抗体 (AA 128-157)
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北京 101111
Quick Overview for RRM2B 抗体 (AA 128-157) (ABIN1537814)
抗原
See all RRM2B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 128-157
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预测反应
- Pr, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RRM2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human RRM2B.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- RRM2B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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别名
- RRM2B
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背景
- This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
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分子量
- 40737
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基因ID
- 50484
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NCBI登录号
- NP_001165948, NP_001165949, NP_056528
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UniProt
- Q7LG56
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途径
- p53 Pathway, Negative Regulation of intrinsic apoptotic Signaling
抗原
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