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GDF15 抗体 (AA 125-151)

This anti-GDF15 antibody is a 兔 多克隆 antibody detecting GDF15 in WB. Suitable for 人.
产品编号 ABIN1537803
发货至: 中国

Quick Overview for GDF15 抗体 (AA 125-151) (ABIN1537803)

抗原

See all GDF15 抗体
GDF15 (Growth Differentiation Factor 15 (GDF15))

适用

  • 116
  • 41
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宿主

  • 106
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克隆类型

  • 103
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多克隆

标记

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This GDF15 antibody is un-conjugated

应用范围

  • 112
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Western Blotting (WB)

克隆位点

RB39612
  • 抗原表位

    • 15
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    • 9
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    • 1
    AA 125-151

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PDF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-151 amino acids from the Central region of human PDF.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    PDF Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    GDF15 (Growth Differentiation Factor 15 (GDF15))

    别名

    PDF

    背景

    Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells.

    分子量

    27013

    基因ID

    64146

    NCBI登录号

    NP_071736

    UniProt

    Q9HBH1

    途径

    SARS-CoV-2 Protein Interactome
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