电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

USP8 抗体 (C-Term)

This anti-USP8 antibody is a Mouse Monoclonal antibody detecting USP8 in WB. Suitable for Human.
产品编号 ABIN1536612
发货至: 中国

Quick Overview for USP8 抗体 (C-Term) (ABIN1536612)

抗原

See all USP8 抗体
USP8 (Ubiquitin Specific Peptidase 8 (USP8))

适用

  • 38
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 35
  • 2
  • 1
小鼠

克隆类型

  • 36
  • 2
单克隆

标记

  • 28
  • 2
  • 2
  • 2
  • 2
  • 2
This USP8 antibody is un-conjugated

应用范围

  • 35
  • 16
  • 15
  • 8
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

460CT35-1-6
  • 抗原表位

    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, C-Term

    预测反应

    M

    纯化方法

    Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

    免疫原

    This USP8 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human USP8.

    亚型

    IgG1
  • 应用备注

    WB: 1:500~4000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    USP8 Antibody (C-term C1072)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

    有效期

    6 months
  • 抗原

    USP8 (Ubiquitin Specific Peptidase 8 (USP8))

    别名

    USP8

    背景

    Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules.

    分子量

    127523

    基因ID

    9101

    NCBI登录号

    NP_001122082, NP_001122083, NP_005145

    UniProt

    P40818
You are here:
Chat with us!