USP8 抗体 (C-Term)
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北京 101111
Quick Overview for USP8 抗体 (C-Term) (ABIN1536612)
抗原
See all USP8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, C-Term
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预测反应
- M
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纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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免疫原
- This USP8 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the C-terminal region of human USP8.
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亚型
- IgG1
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anti-Ubiquitin Specific Peptidase 8 (USP8) antibody
USP8 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 1-270) antibodyUSP8 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 1-270) antibodyUSP8 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 861-910) antibodyUSP8 适用: 人, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 151-200) antibodyUSP8 适用: 人, Pig, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 777-1118) antibodyUSP8 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (AA 1058-1087), (C-Term) antibodyUSP8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB04288 unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (C-Term) antibodyUSP8 适用: 人, 小鼠, Pig, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 8 (USP8) (C-Term) antibodyUSP8 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500~4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- USP8 Antibody (C-term C1072)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- USP8 (Ubiquitin Specific Peptidase 8 (USP8))
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别名
- USP8
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背景
- Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules.
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分子量
- 127523
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基因ID
- 9101
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NCBI登录号
- NP_001122082, NP_001122083, NP_005145
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UniProt
- P40818
抗原
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