MMP12 抗体 (Cleaved-Gly106)
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北京 101111
Quick Overview for MMP12 抗体 (Cleaved-Gly106) (ABIN1536141)
抗原
See all MMP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 87-136, Cleaved-Gly106
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原理
- Cleaved-MMP-12 (G106) Antibody
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特异性
- Cleaved-MMP-12 (G106) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-12 protein resulting from cleavage adjacent to G106.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MMP12. AA range:87-136
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亚型
- IgG
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anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 391-420), (C-Term) antibody
MMP12 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB2026 unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 100-286) antibodyMMP12 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 20-99) antibodyMMP12 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 290-469) antibodyMMP12 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 372-463) antibodyMMP12 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 294-473) antibodyMMP12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 1-470) antibodyMMP12 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 109-470) antibodyMMP12 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) antibodyMMP12 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 201-300) antibodyMMP12 适用: 大鼠 WB, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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别名
- MMP12
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背景
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Synonyms: MMP12, HME, Macrophage metalloelastase, MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12
Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],
Gene Name: MMP12
Protein Name: Macrophage metalloelastase
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分子量
- 42 kDa
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基因ID
- 4321
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OMIM
- 601046
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UniProt
- P39900
抗原
-
