Factor VII 抗体 (Cleaved-Arg212)
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Quick Overview for Factor VII 抗体 (Cleaved-Arg212) (ABIN1536130)
抗原
See all Factor VII (F7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 171-220, Cleaved-Arg212
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原理
- Cleaved-Factor VII LC (R212) Antibody
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特异性
- Cleaved-Factor VII LC (R212) Polyclonal Antibody detects endogenous levels of fragment of activated Factor VII LC protein resulting from cleavage adjacent to R212.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FA7. AA range:171-220
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亚型
- IgG
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anti-Coagulation Factor VII (F7) (AA 42-169) antibody
F7 适用: 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (Internal Region) antibodyF7 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 IHC, ELISA, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 302-332) antibodyF7 适用: 人 WB 宿主: 兔 Polyclonal RB54990 unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 WB, ELISA, RIA 宿主: 小鼠 Monoclonal RFF-VII-1 unconjugated
anti-Coagulation Factor VII (F7) (AA 251-300) antibodyF7 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 173-222) antibodyF7 适用: 人, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Factor VII (F7) (Coagulation Factor VII (F7))
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别名
- FA7
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背景
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Synonyms: F7, Coagulation factor VII, Proconvertin, Serum prothrombin conversion accelerator, SPCA, Eptacog alfa
Background: This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015],
Gene Name: F7
Protein Name: Coagulation factor VII
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分子量
- 17 kDa
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基因ID
- 2155
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OMIM
- 227500
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UniProt
- P08709
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途径
- Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
抗原
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