MASP1 抗体 (Cleaved-Arg448)
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北京 101111
Quick Overview for MASP1 抗体 (Cleaved-Arg448) (ABIN1536127)
抗原
See all MASP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 399-448, Cleaved-Arg448
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原理
- Cleaved-MASP-1 HC (R448) Antibody
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特异性
- Cleaved-MASP-1 HC (R448) Polyclonal Antibody detects endogenous levels of fragment of activated MASP-1 HC protein resulting from cleavage adjacent to R448.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MASP1. AA range:399-448
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亚型
- IgG
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anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 20-447) antibody
MASP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 25-453) antibodyMASP1 适用: 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 20-120) antibodyMASP1 适用: 人 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 1-380) antibodyMASP1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 481-507) antibodyMASP1 适用: 人 WB 宿主: 兔 Polyclonal RB22401 unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (cleaved), (Internal Region) antibodyMASP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 20-699) antibodyMASP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (Arg448), (cleaved) antibodyMASP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (AA 1-380) antibodyMASP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
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别名
- MASP1
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背景
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Synonyms: MASP1, CRARF, CRARF1, PRSS5, Mannan-binding lectin serine protease 1, Complement factor MASP-3, Complement-activating component of Ra-reactive factor, Mannose-binding lectin-associated serine protease 1, MASP-1, Mannose-binding protein-asso
Background: mannan binding lectin serine peptidase 1(MASP1) Homo sapiens This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[p
Gene Name: MASP1
Protein Name: Mannan-binding lectin serine protease 1
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分子量
- 47 kDa
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基因ID
- 5648
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OMIM
- 600521
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UniProt
- P48740
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途径
- Complement System
抗原
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