Caspase 3 抗体 (Cleaved-Asp175)
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Quick Overview for Caspase 3 抗体 (Cleaved-Asp175) (ABIN1536080)
抗原
See all Caspase 3 (CASP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 126-175, Cleaved-Asp175
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原理
- Cleaved-Caspase-3 p17 (D175) Antibody
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特异性
- Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-3 p17 protein resulting from cleavage adjacent to D175.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Caspase 3. AA range:126-175
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亚型
- IgG
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anti-Caspase 3 (CASP3) (AA 60-100) antibody
CASP3 适用: 人, 小鼠, 大鼠, Cow, 山羊 WB, IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 67-175) antibodyCASP3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 (CASP3) antibodyCASP3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 5E1 unconjugated
anti-Caspase 3 (CASP3) (AA 11-120) antibodyCASP3 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 (CASP3) (cleaved) antibodyCASP3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 (CASP3) (C-Term) antibodyCASP3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Caspase 3 (CASP3) (AA 60-90) antibodyCASP3 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14696 unconjugated
anti-Caspase 3 (CASP3) (AA 149-179), (Asp175) antibodyCASP3 适用: 人, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB25834 unconjugated
anti-Caspase 3 (CASP3) (AA 29-175) antibodyCASP3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Caspase 3 (CASP3)
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别名
- Caspase 3
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背景
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Synonyms: CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],
Gene Name: CASP3
Protein Name: Caspase3
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分子量
- 20 kDa
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基因ID
- 836
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OMIM
- 600636
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UniProt
- P42574
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
抗原
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