MC1 Receptor 抗体 (AA 268-317)
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北京 101111
Quick Overview for MC1 Receptor 抗体 (AA 268-317) (ABIN1535779)
抗原
See all MC1 Receptor (MC1R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 268-317
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原理
- MC1-R Antibody
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特异性
- MC1-R Polyclonal Antibody detects endogenous levels of MC1-R protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MSHR. AA range:268-317
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亚型
- IgG
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anti-Melanocortin 1 Receptor (MC1R) (AA 1-37) antibody
MC1R 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibodyMC1R 适用: 小鼠 WB, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R 适用: 人 WB, IF, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (3rd Intracellular Loop), (AA 217-232) antibodyKO Validated MC1R 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) antibodyMC1R 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) antibodyKD Validated MC1R 适用: 人 WB 宿主: 兔 Monoclonal 25GB5955 unconjugated Recombinant Antibody
anti-Melanocortin 1 Receptor (MC1R) (Cytoplasmic Domain) antibodyMC1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibody (AbBy Fluor® 488)MC1R 适用: 小鼠 WB, IF (cc), IF (p), FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
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别名
- MSHR
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背景
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Synonyms: MC1R, MSHR, Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R
Background: This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that this gene is an important component in de
Gene Name: MC1R
Protein Name: Melanocyte-stimulating hormone receptor
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分子量
- 34 kDa
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基因ID
- 4157
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OMIM
- 155555
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UniProt
- Q01726
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途径
- cAMP Metabolic Process, Feeding Behaviour
抗原
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