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GRM7 抗体 (AA 351-400)

This 兔 多克隆 antibody specifically detects GRM7 in WB, ELISA 和 IHC. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1535757
发货至: 中国
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Quick Overview for GRM7 抗体 (AA 351-400) (ABIN1535757)

抗原

See all GRM7 抗体
GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

适用

  • 46
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  • 15
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  • 5
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  • 4
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  • 2
  • 2
  • 1
  • 1
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人, 大鼠, 小鼠

宿主

  • 37
  • 11
  • 1
兔

克隆类型

  • 38
  • 11
多克隆

标记

  • 37
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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This GRM7 antibody is un-conjugated

应用范围

  • 34
  • 17
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  • 9
  • 9
  • 5
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 12
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-400

    原理

    mGluR7 Antibody

    特异性

    MGluR7 Polyclonal Antibody detects endogenous levels of mGluR7 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GRM7. AA range:351-400

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

    别名

    GRM7

    背景

    Synonyms: GRM7, GPRC1G, MGLUR7, Metabotropic glutamate receptor 7, mGluR7

    Background: glutamate metabotropic receptor 7(GRM7) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found

    Gene Name: GRM7

    Protein Name: Metabotropic glutamate receptor 7

    分子量

    102 kDa

    基因ID

    2917

    OMIM

    604101

    UniProt

    Q14831

    途径

    Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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