Metabotropic Glutamate Receptor 1 抗体 (AA 251-300)
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Quick Overview for Metabotropic Glutamate Receptor 1 抗体 (AA 251-300) (ABIN1535754)
抗原
See all Metabotropic Glutamate Receptor 1 (GRM1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-300
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原理
- mGluR1 Antibody
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特异性
- MGluR1 Polyclonal Antibody detects endogenous levels of mGluR1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GRM1. AA range:251-300
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))
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别名
- GRM1
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背景
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Synonyms: GRM1, GPRC1A, MGLUR1, Metabotropic glutamate receptor 1, mGluR1
Background: glutamate metabotropic receptor 1(GRM1) Homo sapiens This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],
Gene Name: GRM1
Protein Name: Metabotropic glutamate receptor 1
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分子量
- 132 kDa
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基因ID
- 2911
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OMIM
- 604473
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UniProt
- Q13255
抗原
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